COMEDY OFF MAIN STREET at 38 S McDonald in Mesa, AZ is your new destination for live comedy. A 50-seat intimate venue, it hosts local and national comics, so be ready to laugh your head off every time you hit it up. So far offering coffee, snacks and light beverages, we will soon have a full liquor license and food menu.If you’re in the Phoenix Metropolitan area such as Scottsdale, Mesa, Tempe or other nearby locales, check out Comedy off Main Street for a night out you’ll not forget. Easy to get to, right off the light rail, in the heart of Downtown Mesa. The line-up for through April is set, also several dates in May, lots of funny acts, check out Show & Tickets to get in on the laughs.

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Comedy will never be the same now that Comedy off Main Street has hit the scene!